Read more about the article GLP OECD 442E h-CLAT – Human Cell Line Activation Test
Skin sensitization Adverse Outcome Pathway (AOP). Dendritic cell activation is identified as Key Event 3 of the AOP and is part of an Integrated Approach to Testing and Assessment (IATA) to support the discrimination between sensitizers (i.e., UN GHS Category 1) and non-sensitizers for the purpose of hazard classification and labeling.

GLP OECD 442E h-CLAT – Human Cell Line Activation Test

GLP OECD 442E h-CLAT Human Cell Line Activation Test Expert Non-Animal Skin Sensitization Testing The Human Cell Line Activation Test (h-CLAT), described in OECD Test Guideline 442E, is a non-animal,…

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