About
Over 50 years of
Toxicology Testing Experience
MB Research Laboratories is a leading Contract Research Organization (CRO) based in Pennsylvania, specializing in short-term toxicology and pharmacology testing services since 1972. With over 50 years of experience, MB Research provides GLP-compliant in vivo and in vitro toxicological testing for a wide range of industries, including pharmaceuticals, biotechnology, medical devices, agrochemicals, and government agencies.
As a pioneer in non-animal testing methods, MB Research has helped clients transition from traditional animal models to alternative testing approaches for over 35 years. Our laboratory offers a comprehensive suite of regulatory toxicology studies, including skin and eye irritation, sensitization, cytotoxicity, genotoxicity, and more—tailored to meet your specific regulatory and product development needs. Our protocols are designed to meet your specific regulatory and product development needs with high quality testing and a rapid turnaround at a competitive price.
Our experienced Study Directors and technical staff are committed to delivering clear, timely, and accurate results for hazard identification and safety assessments. MB Research also offers full-service support including study consultation, custom protocol development, quality assurance, and secure archiving.
Our validated test protocols meet global regulatory standards, including:
- U.S. Environmental Protection Agency (EPA)
- U.S. Food and Drug Administration (FDA)
- U.S. Consumer Product Safety Commission (CPSC)
- U.S. Department of Transportation (DOT)
- Globally Harmonized System (GHS)
- U.S. Pharmacopeia (USP)
- International Organization for Standardization (ISO)
Whether you require traditional toxicology services or cutting-edge New Approach Methodologies (NAMs), MB Research is your trusted partner for reliable, regulatory-ready testing.
For more information about testing capabilities, please click here.
Leading with
Innovation
- BCOP Test: Bovine Corneal Opacity and Permeability Test (OECD 437)
- Corrositex® Assay (OECD 435)
- 3D Human Tissue Models for Ocular and Dermal Irritation/Corrosivity
- In Vitro Sensitization Assay (IVSA) IL-18 from 3D Epidermal Tissues
- h-CLAT: Human Cell Line Activation Test (OECD 442)
- ROBatt - A Tiered Testing Strategy for Ocular Irritation Categorization
- PorCORA - Porcine Corneal Opacity and Reversibility Assay
- 3T3 Neutral Red Uptake Phototoxicity Test (OECD 432)
- Irritection® Ocular Assay (OECD 496)
- Irritection® Dermal Assay (Skin Irritation)
For over 35 years, MB Research has been validating and developing in vitro and alternative tests.
Collaborating with
The Experts
- CellSystems Henkel EpiCS® 3D Skin Model
- L’Oréal’s EPISKIN and SkinEthic™ 3D Skin Models
- National Institute for Environmental Health Sciences
- MatTek EpiVaginal™ 3D Mucosal Tissue Model
- MatTek EpiAirway™ Lung Tissue Model
Accreditations & Regulatory
Compliance
MB Research understands the criticality of complying with various regulatory guidelines and standards. Our team has extensive experience conducting GLP-compliant studies according to:
- US FDA 21 CFR Part 58 Good Laboratory Practices for Nonclinical Laboratory Studies
- US EPA 40 CFR Part 160 Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) Good Laboratory Practice Standards
- US EPA 40 CFR Part 792 Toxic Substances Control Act (TSCA): Good Laboratory Practice Standards
- Organization for Economic Co-operation and Development (OECD) Principles on Good Laboratory Practices
MB Research has been an AAALAC accredited laboratory continuously since 1975 and has a PHS Approved Animal Welfare Assurance.
We regularly host audits from governmental agencies (USDA, FDA and EPA).
MB Research registered with the proper complimentary Commonwealth of Pennsylvania agencies.
