Toxicology Testing Services

MB Research Labs is a contract research organization, with over 40 years of experience in product safety testing for the chemical, consumer products and cosmetics industries.More..
In Vitro and Alternative Toxicology Test Methods that Reduce, Refine or Replace the use of live animals in Product Safety Testings.
MB Research conducts acute, subchronic, chronic and general toxicology studies that are designed to meet regulatory guidelines.
Beauty & Heatlhcare Products. MB Research Labs is often sought out by Cosmetic Industry Leaders to ensure the safety of their ingredients and aid in the rapid development of products.
Our Capabilities List of Toxicological Safety Assessments is available online. For more help, please contact Client Services.
REACH, OECD, COLIPA and 7th Amendment Cosmetic Directive compliant protocols for acute and subchronic toxicology assessments are available.
MB Research has utilized 3D Human Tissue Constructs for many years for ocular and dermal irritation screening for the cosmetic, petrochemical, and pharmaceutical industries. More.

MB Research Labs

Your Trusted Toxicology Testing Partner

Industries Served:

NEW - In Vitro Sensitization ITS

MB Research has teamed with Wildlife International to provide a non-animal Integrated Testing Strategy (ITS) for chemical-induced contact hypersensitivity (skin sensitization). This ITS provides a completely non-animal alternative to traditional testing methods. Together, our three assays address three key events on the skin sensitization adverse outcome pathway (AOP).

IVSA

The In Vitro Sensitization Assay (IVSA) is a keratinocyte activation test. IVSA uses an ELISA method to measure IL-18 release from a topically treated reconstructed 3D human keratinocyte tissue model.

h-CLAT

The Human Cell Line Activation Test (h-CLAT) is a dendritic cell activation test. The h-CLAT uses flow cytometry to measure CD86 and CD54 expression on treated THP-1 cells in culture.

DPRA

The Direct Peptide Reactivity Assay (DPRA) is an in chemico method used to predict epidermal protein binding. Binding of epidermal proteins is the molecular initiating event on the AOP. The DPRA uses HPLC to measure the depletion of synthetic peptides in solution following exposure to test chemicals.

Award Winning Research. Your Trusted Testing Partner.

Call for Quote or for more information about your testing needs:
US 1-215-536-4110

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